The Limitations of Diazepam as a Treatment for Nerve Agent–Induced Seizures and Neuropathology in Rats: Comparison with UBP302

Exposure to nerve agents induces prolonged status epilepticus (SE), causing brain damage or death. Diazepam (DZP) is the current US Food and Drug Administration–approved drug for the cessation of nerve agent–induced SE. Here, we compared the efficacy of DZP with that of UBP302 [(S)-3-(2-carboxybenzy...

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Detaylı Bibliyografya
Asıl Yazarlar: Apland, James P., Aroniadou-Anderjaska, Vassiliki, Figueiredo, Taiza H., Rossetti, Franco, Miller, Steven L., Braga, Maria F. M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2014
Konular:
Drug Discovery and Translational Medicine
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201270/
https://ncbi.nlm.nih.gov/pubmed/25157087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.217299
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