The Limitations of Diazepam as a Treatment for Nerve Agent–Induced Seizures and Neuropathology in Rats: Comparison with UBP302

Exposure to nerve agents induces prolonged status epilepticus (SE), causing brain damage or death. Diazepam (DZP) is the current US Food and Drug Administration–approved drug for the cessation of nerve agent–induced SE. Here, we compared the efficacy of DZP with that of UBP302 [(S)-3-(2-carboxybenzy...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Apland, James P., Aroniadou-Anderjaska, Vassiliki, Figueiredo, Taiza H., Rossetti, Franco, Miller, Steven L., Braga, Maria F. M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Pharmacology and Experimental Therapeutics 2014
Θέματα:
Drug Discovery and Translational Medicine
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201270/
https://ncbi.nlm.nih.gov/pubmed/25157087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.217299
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