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The Limitations of Diazepam as a Treatment for Nerve Agent–Induced Seizures and Neuropathology in Rats: Comparison with UBP302
Exposure to nerve agents induces prolonged status epilepticus (SE), causing brain damage or death. Diazepam (DZP) is the current US Food and Drug Administration–approved drug for the cessation of nerve agent–induced SE. Here, we compared the efficacy of DZP with that of UBP302 [(S)-3-(2-carboxybenzy...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201270/ https://ncbi.nlm.nih.gov/pubmed/25157087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.217299 |
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