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CCMpred—fast and precise prediction of protein residue–residue contacts from correlated mutations

Motivation: Recent breakthroughs in protein residue–residue contact prediction have made reliable de novo prediction of protein structures possible. The key was to apply statistical methods that can distinguish direct couplings between pairs of columns in a multiple sequence alignment from merely co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Seemayer, Stefan, Gruber, Markus, Söding, Johannes
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201158/
https://ncbi.nlm.nih.gov/pubmed/25064567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu500
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