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CCMpred—fast and precise prediction of protein residue–residue contacts from correlated mutations

Motivation: Recent breakthroughs in protein residue–residue contact prediction have made reliable de novo prediction of protein structures possible. The key was to apply statistical methods that can distinguish direct couplings between pairs of columns in a multiple sequence alignment from merely co...

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Bibliografiske detaljer
Main Authors: Seemayer, Stefan, Gruber, Markus, Söding, Johannes
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201158/
https://ncbi.nlm.nih.gov/pubmed/25064567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu500
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