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CCMpred—fast and precise prediction of protein residue–residue contacts from correlated mutations

Motivation: Recent breakthroughs in protein residue–residue contact prediction have made reliable de novo prediction of protein structures possible. The key was to apply statistical methods that can distinguish direct couplings between pairs of columns in a multiple sequence alignment from merely co...

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Autors principals: Seemayer, Stefan, Gruber, Markus, Söding, Johannes
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201158/
https://ncbi.nlm.nih.gov/pubmed/25064567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu500
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