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OP06 METABOLOMIC ANALYSIS OF GLIOBLASTOMA MULTIFORME UPON ARGININE DEPRIVATION TREATMENT
INTRODUCTION: Treatment of glioblastoma (GBM) remains challenging, and metabolic targeting opens novel treatment approaches. Arginine plays a central role in various proliferative cellular reactions, and argininosuccinate synthetase-1 (ASS1) is the rate-limiting enzyme of arginine synthesis. Methyla...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4200987/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou251.6 |
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