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TM-11 METABOLOMIC ANALYSIS OF GLIOBLASTOMA MULTIFORME UPON ARGININE DEPRIVATION TREATMENT

INTRODUCTION: Treatment of glioblastoma (GBM) remains challenging, and metabolic targeting opens novel treatment approaches. Arginine is a semi-essential amino-acid that plays a central role in various proliferative cellular reactions. Argininosuccinate synthetase-1 (ASS1) is the rate-limiting enzym...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Langer, Julia, Elustondo, Fernando Abaitua, Chan, Eric Chun Yong, Antti, Henrik, Want, Elizabeth, ONeill, Kevin, Syed, Nelofer
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218621/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou278.11
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