OP06 METABOLOMIC ANALYSIS OF GLIOBLASTOMA MULTIFORME UPON ARGININE DEPRIVATION TREATMENT

INTRODUCTION: Treatment of glioblastoma (GBM) remains challenging, and metabolic targeting opens novel treatment approaches. Arginine plays a central role in various proliferative cellular reactions, and argininosuccinate synthetase-1 (ASS1) is the rate-limiting enzyme of arginine synthesis. Methyla...

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Main Authors: Langer, Julia K., Chan, Eric Chun Yong, Antti, Henrik, Want, Elizabeth, ONeill, Kevin, Syed, Nelofer
格式: Artigo
語言:Inglês
出版: Oxford University Press 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200987/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou251.6
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