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O03 IDH1 MUTATIONS IN NEURAL STEM CELLS PROMOTE MIGRATION AND INVASION AND ACT SYNERGISTICALLY WITH P53 AND PTEN LOSS IN MURINE TUMOUR CELLS
INTRODUCTION: Over 70% of low- or high grade gliomas carry IDH1 gene mutations. The understanding of the role of IDH mutations in human glioma cells is limited by concomitant genetic and epigenetic modifications in glioma cell lines, making it difficult to precisely dissect the role of IDH in prolif...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Oxford University Press
2014
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4200946/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou250.3 |
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