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IDH1 mutant glioma initiating cells are predisposed to apoptosis under endoplasmic reticulum (ER) stress
Multiple studies have shown that patients with IDH mutant gliomas survive longer than those with IDH wild type gliomas. However, how the IDH mutation confers a better prognosis, is still largely unclear. To study the role of IDH mutation during glioma initiation and growth, we used a mouse model, wh...
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| Publicado no: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5791715/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox238.055 |
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