O11 TRANSCRIPTIONAL PROFILING OF DISTINCT COMPARTMENTS IN HUMAN GLIOBLASTOMA REVEALS KEY DYSREGULATED PATHWAYS

INTRODUCTION: Glioblastoma (GB) is the most common and aggressive primary brain malignancy. Combining fluorescence-guided resection and neuroanatomy, we have identified three distinct compartments: the sub-ependymal zone (SEZ), the tumour mass (T) and the tumour margin (M). METHOD: RNA from T, SEZ a...

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Hauptverfasser: Piccirillo, S.G.M., Spiteri, I., Sottoriva, A., Touloumis, A., Curtis, C., Marioni, J., Tavaér, S., Watts, C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200943/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou250.11
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