P58 BRAIN TUMOUR CELLS CAN SURVIVE AND THRIVE IN THE HYPOXIC SOLID TUMOUR MICROENVIRONMENT

INTRODUCTION: Normal brain tissue is exposed to 5-8% oxygen whilst the average oxygen level within brain tumours is just 1% (hypoxia). Hypoxia is associated with the increased malignancy, invasiveness, and treatment resistance of brain tumours. Paradoxically, hypoxia has also been shown to induce ce...

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Bibliographic Details
Main Authors: Richards, Rosalie, See, Violaine
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200925/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou249.45
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