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P58 BRAIN TUMOUR CELLS CAN SURVIVE AND THRIVE IN THE HYPOXIC SOLID TUMOUR MICROENVIRONMENT
INTRODUCTION: Normal brain tissue is exposed to 5-8% oxygen whilst the average oxygen level within brain tumours is just 1% (hypoxia). Hypoxia is associated with the increased malignancy, invasiveness, and treatment resistance of brain tumours. Paradoxically, hypoxia has also been shown to induce ce...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4200925/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou249.45 |
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