P12 A PHASE I TRIAL OF INTRAVENOUS ONCOLYTIC REOLYSIN(®) IN PATIENTS WITH BRAIN TUMOURS

INTRODUCTION: Oncolytic viruses preferentially replicate in, and kill cancerous cells. REOLYSIN(®) is a proprietary isolate of reovirus type 3 Dearing. In two trials using intralesional administration in gliomas and recurrent brain tumours, REOLYSIN(®) has been well tolerated, with early signs of ef...

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Main Authors: Jebar, A., West, E., Scott, K., Thomson, S., Corns, R., Mathew, R., SivaKumar, G., Coffey, M., Nuovo, G., Rose, A., Ralph, C., Twelves, C., Anthoney, A., Griffin, S., Short, S., Melcher, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200888/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou249.11
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