Curcumin Promotes KLF5 Proteasome Degradation through Downregulating YAP/TAZ in Bladder Cancer Cells

KLF5 (Krüppel-like factor 5) plays critical roles in normal and cancer cell proliferation through modulating cell cycle progression. In this study, we demonstrated that curcumin targeted KLF5 by promoting its proteasome degradation, but not by inhibiting its transcription in bladder cancer cells. We...

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Autors principals: Gao, Yang, Shi, Qi, Xu, Shan, Du, Chong, Liang, Liang, Wu, Kaijie, Wang, Ke, Wang, Xinyang, Chang, Luke S., He, Dalin, Guo, Peng
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200832/
https://ncbi.nlm.nih.gov/pubmed/25170806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150915173
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