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Curcumin Promotes KLF5 Proteasome Degradation through Downregulating YAP/TAZ in Bladder Cancer Cells

KLF5 (Krüppel-like factor 5) plays critical roles in normal and cancer cell proliferation through modulating cell cycle progression. In this study, we demonstrated that curcumin targeted KLF5 by promoting its proteasome degradation, but not by inhibiting its transcription in bladder cancer cells. We...

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Detalhes bibliográficos
Main Authors: Gao, Yang, Shi, Qi, Xu, Shan, Du, Chong, Liang, Liang, Wu, Kaijie, Wang, Ke, Wang, Xinyang, Chang, Luke S., He, Dalin, Guo, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200832/
https://ncbi.nlm.nih.gov/pubmed/25170806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150915173
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