Tolerance of neurite outgrowth to Rho kinase inhibitors decreased by cyclooxygenase-2 inhibitor☆

In this study, PC12 Adh cells and Neuro-2a cells were treated with Rho-associated kinase inhibitors (Y27632 and Fasudil), a cyclooxygenase-1 selective inhibitor (SC560), and a cyclooxygenase-2 inhibitor (NS398). We found that these cells became tolerant to Rho-associated kinase inhibitors, as neurit...

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Detalhes bibliográficos
Main Authors: Duan, Weigang, Que, Ling, Lv, Xiaoman, Li, Qifeng, Yin, Hua, Zhang, Luyong
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2012
Assuntos:
Stem Cells and Neural Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200739/
https://ncbi.nlm.nih.gov/pubmed/25337117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1673-5374.2012.34.008
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