Anti-proliferative but not anti-angiogenic tyrosine kinase inhibitors enrich for cancer stem cells in soft tissue sarcoma

BACKGROUND: Increasing studies implicate cancer stem cells (CSCs) as the source of resistance and relapse following conventional cytotoxic therapies. Few studies have examined the response of CSCs to targeted therapies, such as tyrosine kinase inhibitors (TKIs). We hypothesized that TKIs would have...

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Detaylı Bibliyografya
Asıl Yazarlar: Canter, Robert J, Ames, Erik, Mac, Stephanie, Grossenbacher, Steven K, Chen, Mingyi, Li, Chin-Shang, Borys, Dariusz, Smith, Rachel C, Tellez, Joe, Sayers, Thomas J, Monjazeb, Arta M, Murphy, William J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200119/
https://ncbi.nlm.nih.gov/pubmed/25301268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-756
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