Anti-proliferative but not anti-angiogenic tyrosine kinase inhibitors enrich for cancer stem cells in soft tissue sarcoma

BACKGROUND: Increasing studies implicate cancer stem cells (CSCs) as the source of resistance and relapse following conventional cytotoxic therapies. Few studies have examined the response of CSCs to targeted therapies, such as tyrosine kinase inhibitors (TKIs). We hypothesized that TKIs would have...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Canter, Robert J, Ames, Erik, Mac, Stephanie, Grossenbacher, Steven K, Chen, Mingyi, Li, Chin-Shang, Borys, Dariusz, Smith, Rachel C, Tellez, Joe, Sayers, Thomas J, Monjazeb, Arta M, Murphy, William J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200119/
https://ncbi.nlm.nih.gov/pubmed/25301268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-756
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