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Phase I Trial of Neoadjuvant Conformal Radiotherapy plus Sorafenib for Patients with Locally Advanced Soft Tissue Sarcoma of the Extremity

INTRODUCTION: Despite effective local therapy with surgery and radiation (RT), approximately 50% of patients with high grade soft tissue sarcoma (STS) will relapse and die of disease. Since experimental data suggest a significant synergistic effect when anti-angiogenic targeted therapies, such as so...

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Détails bibliographiques
Auteurs principaux: Canter, Robert J., Borys, Dariusz, Olusanya, Abimbola, Li, Chin-Shang, Lee, Li-Yuan, Boutin, Robert D., Christensen, Scott D., Tamurian, Robert M., Monjazeb, Arta M.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153793/
https://ncbi.nlm.nih.gov/pubmed/24554062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-014-3543-7
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