Two nuclear localization signals present in the basic-helix 1 domains of MyoD promote its active nuclear translocation and can function independently.

MyoD, a member of the family of helix-loop-helix myogenic factors that plays a crucial role in skeletal muscle differentiation, is a nuclear phosphoprotein. Using microinjection of purified MyoD protein into rat fibroblasts, we show that the nuclear import of MyoD is a rapid and active process, bein...

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Bibliografiska uppgifter
Huvudupphovsmän: Vandromme, M, Cavadore, J C, Bonnieu, A, Froeschlé, A, Lamb, N, Fernandez, A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC42001/
https://ncbi.nlm.nih.gov/pubmed/7753857
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