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Two nuclear localization signals present in the basic-helix 1 domains of MyoD promote its active nuclear translocation and can function independently.

MyoD, a member of the family of helix-loop-helix myogenic factors that plays a crucial role in skeletal muscle differentiation, is a nuclear phosphoprotein. Using microinjection of purified MyoD protein into rat fibroblasts, we show that the nuclear import of MyoD is a rapid and active process, bein...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vandromme, M, Cavadore, J C, Bonnieu, A, Froeschlé, A, Lamb, N, Fernandez, A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1995
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC42001/
https://ncbi.nlm.nih.gov/pubmed/7753857
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