The Myostatin Gene Is a Downstream Target Gene of Basic Helix-Loop-Helix Transcription Factor MyoD

Myostatin is a negative regulator of myogenesis, and inactivation of myostatin leads to heavy muscle growth. Here we have cloned and characterized the bovine myostatin gene promoter. Alignment of the upstream sequences shows that the myostatin promoter is highly conserved during evolution. Sequence...

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Main Authors: Spiller, Michael P., Kambadur, Ravi, Jeanplong, Ferenc, Thomas, Mark, Martyn, Julie K., Bass, John J., Sharma, Mridula
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2002
主題:
Gene Expression
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC139803/
https://ncbi.nlm.nih.gov/pubmed/12242286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7066-7082.2002
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