The Myostatin Gene Is a Downstream Target Gene of Basic Helix-Loop-Helix Transcription Factor MyoD

Myostatin is a negative regulator of myogenesis, and inactivation of myostatin leads to heavy muscle growth. Here we have cloned and characterized the bovine myostatin gene promoter. Alignment of the upstream sequences shows that the myostatin promoter is highly conserved during evolution. Sequence...

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Detalhes bibliográficos
Main Authors: Spiller, Michael P., Kambadur, Ravi, Jeanplong, Ferenc, Thomas, Mark, Martyn, Julie K., Bass, John J., Sharma, Mridula
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139803/
https://ncbi.nlm.nih.gov/pubmed/12242286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7066-7082.2002
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