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The Myostatin Gene Is a Downstream Target Gene of Basic Helix-Loop-Helix Transcription Factor MyoD

Myostatin is a negative regulator of myogenesis, and inactivation of myostatin leads to heavy muscle growth. Here we have cloned and characterized the bovine myostatin gene promoter. Alignment of the upstream sequences shows that the myostatin promoter is highly conserved during evolution. Sequence...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Spiller, Michael P., Kambadur, Ravi, Jeanplong, Ferenc, Thomas, Mark, Martyn, Julie K., Bass, John J., Sharma, Mridula
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139803/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12242286/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.20.7066-7082.2002
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