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Host STAT2/type I interferon axis controls tumor growth

The role of STAT2 in mediating the antigrowth effects of type I interferon (IFN) is well-documented in vitro. Yet evidence of IFN-activated STAT2 as having tumor suppressor function in vivo and participation in antitumor immunity is lacking. Here we show in a syngeneic tumor transplantation model th...

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Detalhes bibliográficos
Main Authors: Yue, Chanyu, Xu, Jun, Estioko, Marc Daryl Tan, Kotredes, Kevin P., Lopez-Otalora, Yolanda, Hilliard, Brendan A., Baker, Darren P., Gallucci, Stefania, Gamero, Ana M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199898/
https://ncbi.nlm.nih.gov/pubmed/24895110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29004
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