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PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells

PCTAIRE1 is distant relative of the cyclin-dependent kinase family that has been implicated in spermatogenesis and neuronal development, but it has not been studied in cancer. Here we report that PCTAIRE1 is expressed in prostate, breast, and cervical cancer cells where its RNAi-mediated silencing c...

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Hlavní autoři: Yanagi, Teruki, Krajewska, Maryla, Matsuzawa, Shu-ichi, Reed, John C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199897/
https://ncbi.nlm.nih.gov/pubmed/25205104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0872
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