Targeting the Wee1 Kinase for Treatment of Pediatric Down Syndrome Acute Myeloid Leukemia

BACKGROUND: Most Down syndrome children with acute myeloid leukemia (DS-AML) have an overall excellent prognosis, however, patients who suffer an induction failure or relapse, have an extremely poor prognosis. Hence, new therapies need to be developed for this subgroup of DS-AML patients. One new th...

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Huvudupphovsmän: Caldwell, J. Timothy, Edwards, Holly, Buck, Steven A., Ge, Yubin, Taub, Jeffrey W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199830/
https://ncbi.nlm.nih.gov/pubmed/24962331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.25081
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