Performance of the Cas9 Nickase System in Drosophila melanogaster

Recent studies of the Cas9/sgRNA system in Drosophila melanogaster genome editing have opened new opportunities to generate site-specific mutant collections in a high-throughput manner. However, off-target effects of the system are still a major concern when analyzing mutant phenotypes. Mutations co...

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Hlavní autoři: Ren, Xingjie, Yang, Zhihao, Mao, Decai, Chang, Zai, Qiao, Huan-Huan, Wang, Xia, Sun, Jin, Hu, Qun, Cui, Yan, Liu, Lu-Ping, Ji, Jun-Yuan, Xu, Jiang, Ni, Jian-Quan
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2014
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Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199701/
https://ncbi.nlm.nih.gov/pubmed/25128437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.114.013821
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