Early Double-Negative Thymocyte Export in Trypanosoma cruzi Infection Is Restricted by Sphingosine Receptors and Associated with Human Chagas Disease

The protozoan parasite Trypanosoma cruzi is able to target the thymus and induce alterations of the thymic microenvironmental and lymphoid compartments. Acute infection results in severe atrophy of the organ and early release of immature thymocytes into the periphery. To date, the pathophysiological...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Lepletier, Ailin, de Almeida, Liliane, Santos, Leonardo, da Silva Sampaio, Luzia, Paredes, Bruno, González, Florencia Belén, Freire-de-Lima, Célio Geraldo, Beloscar, Juan, Bottasso, Oscar, Einicker-Lamas, Marcelo, Pérez, Ana Rosa, Savino, Wilson, Morrot, Alexandre
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2014
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199546/
https://ncbi.nlm.nih.gov/pubmed/25330249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003203
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