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Cytoplasmic Localization of Nucleophosmin in Bone Marrow Blasts of Acute Myeloid Leukemia Patients is not Completely Concordant with NPM1 Mutation and is not Predictive of Prognosis
BACKGROUND: NPM1 mutations are reported to predict a favorable prognosis in acute myeloid leukemia (AML) patients. Aberrant cytoplasmic localization of NPM protein is reported be a surrogate for NPM1 gene mutation. METHODS: Using immunohistochemical analysis (IHC), we assessed for NPM (clone 376) ex...
Gorde:
| Egile Nagusiak: | , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4199225/ https://ncbi.nlm.nih.gov/pubmed/19637342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24543 |
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