HCMV IE2-mediated inhibition of HAT activity downregulates p53 function

Targeting of cellular histone acetyltransferases (HATs) by viral proteins is important in the development of virus-associated diseases. The immediate-early 2 protein (IE2) of human cytomegalovirus (HCMV) binds to the tumor suppressor, p53, and inactivates its functions by unknown mechanisms. Here, w...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:EMBO J
Huvudupphovsmän: Hsu, Chih-Hung, Chang, Margaret D T, Tai, Kang-Yu, Yang, Yu-Ting, Wang, Pei-Shan, Chen, Chi-Ju, Wang, Yan-Hsiung, Lee, Sheng-Chung, Wu, Cheng-Wen, Juan, Li-Jung
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2004
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419916/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15141169/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600239
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk