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HCMV IE2-mediated inhibition of HAT activity downregulates p53 function
Targeting of cellular histone acetyltransferases (HATs) by viral proteins is important in the development of virus-associated diseases. The immediate-early 2 protein (IE2) of human cytomegalovirus (HCMV) binds to the tumor suppressor, p53, and inactivates its functions by unknown mechanisms. Here, w...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419916/ https://ncbi.nlm.nih.gov/pubmed/15141169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600239 |
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