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Activation of a DNA Damage Checkpoint Response in a TAF1-Defective Cell Line

Although the link between transcription and DNA repair is well established, defects in the core transcriptional complex itself have not been shown to elicit a DNA damage response. Here we show that a cell line with a temperature-sensitive defect in TBP-associated factor 1 (TAF1), a component of the...

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Detalhes bibliográficos
Main Authors: Buchmann, Ann M., Skaar, Jeffrey R., DeCaprio, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419897/
https://ncbi.nlm.nih.gov/pubmed/15169897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.12.5332-5339.2004
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