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Activation of a DNA Damage Checkpoint Response in a TAF1-Defective Cell Line

Although the link between transcription and DNA repair is well established, defects in the core transcriptional complex itself have not been shown to elicit a DNA damage response. Here we show that a cell line with a temperature-sensitive defect in TBP-associated factor 1 (TAF1), a component of the...

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Udgivet i:Mol Cell Biol
Principais autores: Buchmann, Ann M., Skaar, Jeffrey R., DeCaprio, James A.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2004
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419897/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15169897/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.12.5332-5339.2004
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