A PH domain in ACAP1 possesses key features of the BAR domain in promoting membrane curvature

The BAR (Bin-Amphiphysin-Rvs) domain undergoes dimerization to produce a curved protein structure, which superimposes onto membrane through electrostatic interactions to sense and impart membrane curvature. In some cases, a BAR domain also possesses an amphipathic helix that inserts into the membran...

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Main Authors: Pang, Xiaoyun, Fan, Jun, Zhang, Yan, Zhang, Kai, Gao, Bingquan, Ma, Jun, Li, Jian, Deng, Yuchen, Zhou, Qiangjun, Egelman, Edward H., Hsu, Victor W., Sun, Fei
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198613/
https://ncbi.nlm.nih.gov/pubmed/25284369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.08.020
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