Multifunctional Liposomes Reduce Brain β-Amyloid Burden and Ameliorate Memory Impairment in Alzheimer's Disease Mouse Models

Alzheimer's disease is characterized by the accumulation and deposition of plaques of β-amyloid (Aβ) peptide in the brain. Given its pivotal role, new therapies targeting Aβ are in demand. We rationally designed liposomes targeting the brain and promoting the disaggregation of Aβ assemblies and...

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Autors principals: Balducci, Claudia, Mancini, Simona, Minniti, Stefania, La Vitola, Pietro, Zotti, Margherita, Sancini, Giulio, Mauri, Mario, Cagnotto, Alfredo, Colombo, Laura, Fiordaliso, Fabio, Grigoli, Emanuele, Salmona, Mario, Snellman, Anniina, Haaparanta-Solin, Merja, Forloni, Gianluigi, Masserini, Massimo, Re, Francesca
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2014
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198543/
https://ncbi.nlm.nih.gov/pubmed/25319699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0284-14.2014
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