In vivo PET imaging of beta-amyloid deposition in mouse models of Alzheimer's disease with a high specific activity PET imaging agent [(18)F]flutemetamol

BACKGROUND: The purpose of the study was to evaluate the applicability of (18)F-labelled amyloid imaging positron emission tomography (PET) agent [(18)F]flutemetamol to detect changes in brain beta-amyloid (Aβ) deposition in vivo in APP23, Tg2576 and APPswe-PS1dE9 mouse models of Alzheimer's di...

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Vydáno v:EJNMMI Res
Hlavní autoři: Snellman, Anniina, Rokka, Johanna, López-Picón, Francisco R, Eskola, Olli, Salmona, Mario, Forloni, Gianluigi, Scheinin, Mika, Solin, Olof, Rinne, Juha O, Haaparanta-Solin, Merja
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer 2014
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412375/
https://ncbi.nlm.nih.gov/pubmed/25977876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-014-0037-3
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