Multifunctional Liposomes Reduce Brain β-Amyloid Burden and Ameliorate Memory Impairment in Alzheimer's Disease Mouse Models

Alzheimer's disease is characterized by the accumulation and deposition of plaques of β-amyloid (Aβ) peptide in the brain. Given its pivotal role, new therapies targeting Aβ are in demand. We rationally designed liposomes targeting the brain and promoting the disaggregation of Aβ assemblies and...

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Detalhes bibliográficos
Main Authors: Balducci, Claudia, Mancini, Simona, Minniti, Stefania, La Vitola, Pietro, Zotti, Margherita, Sancini, Giulio, Mauri, Mario, Cagnotto, Alfredo, Colombo, Laura, Fiordaliso, Fabio, Grigoli, Emanuele, Salmona, Mario, Snellman, Anniina, Haaparanta-Solin, Merja, Forloni, Gianluigi, Masserini, Massimo, Re, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198543/
https://ncbi.nlm.nih.gov/pubmed/25319699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0284-14.2014
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