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Recombinant TAT-Gelonin Fusion Toxin: Synthesis and Characterization of Heparin/Protamine-Regulated Cell Transduction

Protein toxins, such as gelonin, are highly desirable anti-cancer drug candidates due to their unparalleled potency and repetitive reaction mechanism in inhibiting protein translation. However, for its potential application in cancer therapy, there remains the cell membrane barrier that allows perme...

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Bibliografiske detaljer
Main Authors: Shin, Meong Cheol, Zhao, Jingwen, Zhang, Jian, Huang, Yongzhuo, He, Huining, Wang, Mei, Min, Kyoung Ah, Yang, Victor C.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198515/
https://ncbi.nlm.nih.gov/pubmed/24733757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.35188
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