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Recombinant TAT-Gelonin Fusion Toxin: Synthesis and Characterization of Heparin/Protamine-Regulated Cell Transduction

Protein toxins, such as gelonin, are highly desirable anti-cancer drug candidates due to their unparalleled potency and repetitive reaction mechanism in inhibiting protein translation. However, for its potential application in cancer therapy, there remains the cell membrane barrier that allows perme...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shin, Meong Cheol, Zhao, Jingwen, Zhang, Jian, Huang, Yongzhuo, He, Huining, Wang, Mei, Min, Kyoung Ah, Yang, Victor C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198515/
https://ncbi.nlm.nih.gov/pubmed/24733757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.35188
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