Slug regulates E‐cadherin repression via p19Arf in prostate tumorigenesis

SLUG represses E‐cadherin to promote epithelial–mesenchymal transition (EMT) in various cancers. Mechanisms that regulate SLUG/E‐cadherin pathway remain poorly understood, especially during tumorigenesis in vivo. Here we report that p19Arf (p14ARF in human) stabilizes Slug to inhibit E‐cadherin in p...

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Autores principales: Xie, Yingqiu, Liu, Shenji, Lu, Wenfu, Yang, Qing, Williams, Kieosha D., Binhazim, Awadh A., Carver, Brett S., Matusik, Robert J., Chen, Zhenbang
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2014
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198473/
https://ncbi.nlm.nih.gov/pubmed/24910389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.05.006
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