Novel tetra-peptide insertion in Gag-p6 ALIX-binding motif in HIV-1 subtype C associated with protease inhibitor failure

A novel tetra-peptide insertion was identified in Gag-p6 ALIX-binding region which is appears in protease inhibitor (PI) failure Indian HIV-1C sequences (Odds Ratio 17.1, p<0.001) but naturally present in half of untreated Ethiopian sequences. The insertion will probably restore the ALIX mediated...

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Detaylı Bibliyografya
Asıl Yazarlar: Neogi, Ujjwal, RAO, Shwetha D, BONTELL, Irene, VERHEYEN, Jens, RAO, Vasudev R, GORE, Sagar C, SONI, Neelesh, SHET, Anita, SCHÜLTER, Eugen, EKSTRAND, Maria L., WONDWOSSEN, Amogne, KAISER, Rolf, MADHUSUDHAN, Mallur S., PRASAD, Vinayaka R, SONNERBORG, Anders
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198440/
https://ncbi.nlm.nih.gov/pubmed/25102091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000419
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