Chromatin Immunoprecipitation Indirect Peaks Highlight Long-Range Interactions of Insulator Proteins and Pol II Pausing

Eukaryotic chromosomes are partitioned into topologically associating domains (TADs) that are demarcated by distinct insulator-binding proteins (IBPs) in Drosophila. Whether IBPs regulate specific long-range contacts and how this may impact gene expression remains unclear. Here we identify ‘indirect...

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Hauptverfasser: Liang, Jun, Lacroix, Laurent, Gamot, Adrien, Cuddapah, Suresh, Queille, Sophie, Lhoumaud, Priscillia, Lepetit, Pierre, Martin, Pascal G.P., Vogelmann, Jutta, Court, Franck, Hennion, Magali, Micas, Gaël, Urbach, Serge, Bouchez, Olivier, Nöllmann, Marcelo, Zhao, Keji, Emberly, Eldon, Cuvier, Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198380/
https://ncbi.nlm.nih.gov/pubmed/24486021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.12.029
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