Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes

RNA polymerase II (RNAPII) pausing/termination shortly after initiation is a hallmark of gene regulation. Here, we show that negative elongation factor (NELF) interacts with Integrator complex subunits (INTScom), RNAPII and Spt5. The interaction between NELF and INTScom subunits is RNA and DNA indep...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Stadelmayer, Bernd, Micas, Gaël, Gamot, Adrien, Martin, Pascal, Malirat, Nathalie, Koval, Slavik, Raffel, Raoul, Sobhian, Bijan, Severac, Dany, Rialle, Stéphanie, Parrinello, Hugues, Cuvier, Olivier, Benkirane, Monsef
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263189/
https://ncbi.nlm.nih.gov/pubmed/25410209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6531
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados