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An alteration in ATG16L1 stability in Crohn disease
Individuals who harbor a common coding polymorphism (Thr300Ala) within a structurally unclassified region of ATG16L1 are at increased risk for the development of Crohn disease. Recently, we reported on the generation and characterization of knockin mice carrying the ATG16L1 T300A variant. We demonst...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4198368/ https://ncbi.nlm.nih.gov/pubmed/25136803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.29963 |
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