Role of arterial telomere dysfunction in hypertension: relative contributions of telomere shortening and telomere uncapping

OBJECTIVE: Telomere shortening in arteries could lead to telomere uncapping and cellular senescence, which in turn could promote the development of hypertension. METHODS AND RESULTS: To assess the novel role of arterial telomere dysfunction in hypertension, we compared mean telomere length (qPCR), t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Morgan, R. Garrett, Ives, Stephen J., Walker, Ashley E., Cawthon, Richard M., Andtbacka, Robert H.I., Noyes, Dirk, Lesniewski, Lisa A., Richardson, Russell S., Donato, Anthony J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198301/
https://ncbi.nlm.nih.gov/pubmed/24686009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0000000000000157
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