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Identification of a Novel Lysosomal Trafficking Peptide using Phage Display Biopanning Coupled with Endocytic Selection Pressure

[Image: see text] Methods to select ligands that accumulate specifically in cancer cells and traffic through a defined endocytic pathway may facilitate rapid pairing of ligands with linkers suitable for drug conjugate therapies. We performed phage display biopanning on cancer cells that are treated...

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Autors principals: Umlauf, Benjamin J., Mercedes, Julia S, Chung, Chin-Ying, Brown, Kathlynn C.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198098/
https://ncbi.nlm.nih.gov/pubmed/25188559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc500326x
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