MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures

Fibroblasts can be directly reprogrammed into cardiomyocyte-like cells (iCMs) by overexpression of cardiac transcription factors or microRNAs. However, induction of functional cardiomyocytes is inefficient, and molecular mechanisms of direct reprogramming remain undefined. Here, we demonstrate that...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Muraoka, Naoto, Yamakawa, Hiroyuki, Miyamoto, Kazutaka, Sadahiro, Taketaro, Umei, Tomohiko, Isomi, Mari, Nakashima, Hanae, Akiyama, Mizuha, Wada, Rie, Inagawa, Kohei, Nishiyama, Takahiko, Kaneda, Ruri, Fukuda, Toru, Takeda, Shu, Tohyama, Shugo, Hashimoto, Hisayuki, Kawamura, Yoshifumi, Goshima, Naoki, Aeba, Ryo, Yamagishi, Hiroyuki, Fukuda, Keiichi, Ieda, Masaki
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2014
Teme:
Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198052/
https://ncbi.nlm.nih.gov/pubmed/24920580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201387605
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items