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Estrogen Receptor Inhibits Mineralocorticoid Receptor Transcriptional Regulatory Function
The steroid hormone aldosterone (aldo) contributes to cardiovascular disease in animal models and in humans. Aldo activates the mineralocorticoid receptor (MR), a hormone-activated transcription factor, and indeed, pharmacological MR inhibition improves cardiovascular outcomes. Because the incidence...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Endocrine Society
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197987/ https://ncbi.nlm.nih.gov/pubmed/25051445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1270 |
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