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Aldosterone promotes vascular remodeling by direct effects on smooth muscle cell mineralocorticoid receptors

OBJECTIVE: Vascular remodeling occurs after endothelial injury resulting in smooth muscle cell (SMC) proliferation and vascular fibrosis. We previously demonstrated that the blood pressure-regulating hormone aldosterone enhances vascular remodeling in mice at sites of endothelial injury in a placent...

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Detalhes bibliográficos
Main Authors: Pruthi, Dafina, McCurley, Amy, Aronovitz, Mark, Galayda, Carol, Karumanchi, S. Ananth, Jaffe, Iris Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951242/
https://ncbi.nlm.nih.gov/pubmed/24311380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302854
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